Biostatistician II – Center for Data Driven Discovery

Job Details:-

This is a job posting from company – CHOP

Employment TypeFull Time

Work Hours: 8

Salary: $20 To $30/An Hour

Location: Pennsylvania, USA

This job is 100% remote.

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​Location: LOC_HOME-Home/Remote Office Location

Req ID: 220671

Shift: Days

Employment Status: Regular – Full Time

​About Us
We’re seeking breakthrough makers! Children’s Hospital of Philadelphia was built on the belief that we can change lives. Today, in every role throughout our hospital, research institute and care network, the 22,000 members of our workforce are finding new ways – big and small – to make a difference for the patients and families we serve.

If you are ready to challenge yourself, be inspired and grow – no matter what your role – you just may be the kind of breakthrough maker who will thrive at CHOP.

​CHOP is proud to share that we are ranked No. 1 on Forbes’ 2022 list of America’s Best Large Employers!

Job Summary

The Center for Data Driven Discovery (D3b) at The Children’s Hospital of Philadelphia (CHOP) is seeking a Biostatistician II to join a diverse team of research professionals and to work partner with our more than 30 professional data engineers, developers, data scientists, bioinformatics engineers and bioinformatics scientists committed to accelerating cures for children with cancer and rare diseases. You will be involved in brain tumor research and clinical trial projects characterized with multiple next-generation sequencing or microarray technologies (WGS, WXS, Targeted Panel, RNA-Seq, miRNA, methylation, proteomics, scRNA-Seq) as well as radiology imaging and multi-modal research utilizing AI and machine learning methods.

The candidate will focus on the development of novel methods to implement genomics-driven therapy recommendations for rare pediatric central nervous system tumors that have been characterized as part of an NCI-funded Molecular Characterization Initiative, the Children’s Brain Tumor Network (CBTN), and Pacific Pediatric Neuro-oncology (PNOC) clinical trials. The primary goal of this initiative will be to support precision medicine and clinical decision efforts as part of our ongoing pediatric oncology trials and internal molecular tumor boards for clinical diagnostics. Additionally, the candidate will focus on the development and application of multivariate analysis and novel machine learning methods to predict outcomes of interest, such as prognosis or diagnosis for the patients, based on radiological image features and/or other -omic features such as genomic, proteomic, or immunomic markers.

Job Responsibilities Overview

The responsibilities of this role include the development of predictive models for clinical decision making, the use of real-world data for the design of synthetic control arms, and reporting clinically relevant findings and their interpretation for clinician stakeholders through data visualization and written communications. The candidate will be actively involved throughout the entire process of ongoing research projects, from the study design stage (by performing power analysis and providing design advice prior to the start of the project and patient recruitment to properly evaluate the research hypothesis proposed by the investigator) through development of statistical approaches required during the project and the subsequent reporting of findings. They will further contribute to preparation of grant proposals, manuscripts, conference abstracts/papers or presentations.

The Biostatistician II is a moderately independent role that builds upon an entry level position based on demonstrated increase in consistent proficiency of methods application, programming, interpretation, and communication. This role provides advanced biostatistical services for investigators, including analyses, data preparation, and writing of statistical results on an increasingly independent level, working closely with senior biostatistician and data science team members.

The role will work under the supervision of the D3b Scientific Director, and the technical director of the Clinical and Translational Data Science unit in support of a cross Unit environment. D3b is a highly collaborative environment, and the selected candidate is expected to cooperate as a team player and actively participate in regular meetings and discussions to share their feedback and input on ongoing or new projects.

Required Education and Experience

Required Education: Bachelor’s degree

Required Experience:

  • Three (3) years of experience with progressively more complex applied statistics.
  • Three (3) years applied experience in using one or more common statistical language programs

Preferred Education, Experience & Cert/Lic

Preferred Education: Master’s degree

Preferred Experience:

  • Five (5) years of experience with progressively more complex applied statistics.
  • Five (5) years applied experience in using one or more common statistical language programs

Additional Technical Requirements

  • Proficient in programming and application of common statistical methods in medical and clinical research, such as SAS, STATA, R, Python, or another commonly accepted analytical programming language.
  • Excellent verbal and written communications skills with the demonstrated ability to explain technical concepts to a lay audience.
  • Detail-oriented with excellent validation and documentation skills.
  • High level of personal initiative; ability to work independently as well as collaborate in teams and with people from multiple business and scientific areas.

To carry out its mission, it is of critical importance for the Children’s Hospital of Philadelphia (CHOP) to keep our patients, families and workforce safe and healthy and to support the health of our global community. In keeping with this, CHOP has mandated all workforce members on site at any CHOP location for any portion of their time be vaccinated for COVID-19 as a condition of employment. This mandate also applies to workforce members performing work for CHOP at non-CHOP locations. Additionally, all workforce members based in or regularly scheduled to work at any New Jersey location are mandated to be both vaccinated and boosted for COVID-19, with booster timing consistent with applicable guidelines. The CHOP COVID-19 vaccine mandate is in alignment with applicable local, state and federal mandates. CHOP also requires all workforce members who work in patient care buildings or who provide patient care to receive an annual influenza vaccine. Employees may request exemption consideration for CHOP vaccine requirements for valid religious and medical reasons. Please note start dates may be delayed until candidates are fully immunized or valid exemption requests are reviewed. In addition, candidates other than those in positions with regularly scheduled hours in New Jersey, must attest to not using tobacco products.
EEO / VEVRAA Federal Contractor


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